loading...| Preferred Name | Primary lateral sclerosis | |
| Synonyms |
PLS Adult-onset PLS Adult-onset primary lateral sclerosis |
|
| Definitions |
Primary lateral sclerosis (PLS) is an idiopathic non-familial motor neuron disease characterized by slowly progressive upper motor neuron dysfunction leading to spasticity, mild weakness in voluntary muscle movement, hyperreflexia, and loss of motor speech production. |
|
| ID |
http://www.orpha.net/ORDO/Orphanet_35689 |
|
| alternative_term |
PLS Adult-onset PLS Adult-onset primary lateral sclerosis |
|
| definition |
Primary lateral sclerosis (PLS) is an idiopathic non-familial motor neuron disease characterized by slowly progressive upper motor neuron dysfunction leading to spasticity, mild weakness in voluntary muscle movement, hyperreflexia, and loss of motor speech production. |
|
| definition_citation |
Orphanet |
|
| expertlink |
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=en&Expert=35689 |
|
| has_age_of_onset |
Adult Elderly |
|
| has_inheritance |
Not applicable Autosomal recessive Autosomal dominant |
|
| hasDbXref |
ICD-10:G12.2 ICD-11:8B60.4 UMLS:C0154682 MedDRA:10036704 OMIM:611637 |
|
| label |
Primary lateral sclerosis |
|
| notation |
ORPHA:35689 |
|
| part_of |
http://www.orpha.net/ORDO/Orphanet_183500 |
|
| prefixIRI |
ORDO:Orphanet_35689 |
|
| prefLabel |
Primary lateral sclerosis |
|
| present_in |
Europe AND has_point_prevalence_average_value : 1.5 AND has_point_prevalence_range : 1-9 / 100 000 |
|
| treeView |
http://www.orpha.net/ORDO/Orphanet_183500 |
|
| subClassOf |