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Orphanet Rare Disease Ontology
| Preferred Name | African trypanosomiasis | |
| Synonyms |
Sleeping sickness |
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| Definitions |
A rare parasitic disease characterized by infection with the protozoans <i>Trypanosoma brucei rhodesiense</i> (East African trypanosomiasis) or <i>T. brucei gambiense</i> (West African trypanosomiasis), usually due to the bite of an infected tsetse fly. The first, hemolymphatic stage presents with fever, headaches, fatigue, lymphadenopathy, and aching muscles and joints. In East African trypanosomiasis, the fly bite may develop into a red sore or chancre. This form then progresses to CNS invasion with somnolence and other neurologic and psychiatric symptoms within a few weeks, while West African trypanosomiasis slowly progresses within about 3 years. Both forms are fatal if left untreated. |
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| ID |
http://www.orpha.net/ORDO/Orphanet_3385 |
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| alternative_term |
Sleeping sickness
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|
| definition |
A rare parasitic disease characterized by infection with the protozoans <i>Trypanosoma brucei rhodesiense</i> (East African trypanosomiasis) or <i>T. brucei gambiense</i> (West African trypanosomiasis), usually due to the bite of an infected tsetse fly. The first, hemolymphatic stage presents with fever, headaches, fatigue, lymphadenopathy, and aching muscles and joints. In East African trypanosomiasis, the fly bite may develop into a red sore or chancre. This form then progresses to CNS invasion with somnolence and other neurologic and psychiatric symptoms within a few weeks, while West African trypanosomiasis slowly progresses within about 3 years. Both forms are fatal if left untreated.
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| definition_citation |
Orphanet
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| expertlink |
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=en&Expert=3385 |
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| has_age_of_onset |
All ages
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| has_inheritance |
Not applicable
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| hasDbXref |
MedDRA:10001461 ICD-10:B56.1 MeSH:D014353 ICD-10:B56.0 ICD-10:B56.9 ICD-11:1F51 UMLS:C0041228
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| label |
African trypanosomiasis
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| notation |
ORPHA:3385
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| part_of | ||
| prefixIRI |
ORDO:Orphanet_3385
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| prefLabel |
African trypanosomiasis
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| present_in |
Worldwide AND has_point_prevalence_range : Unknown
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| treeView | ||
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