Orphanet Rare Disease Ontology

Last uploaded: July 3, 2024
Preferred Name

Tropical spastic paraparesis

Synonyms

HTLV-1-associated myelopathy/tropical spastic paraparesis

TSP

HAM/TSP

Human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis

Human T-lymphotropic virus type-1-associated myelopathy/tropical spastic paraparesis

Definitions

Tropical spastic paraparesis is a chronic systemic immune-mediated inflammatory myeloneuropathy, more frequently reported in women than in men, that usually presents in adulthood with slowly progressive spastic paraparesis of the lower limbs, bladder and bowel dysfunction, and sensory disturbances in the lower extremities (e.g. paresthesia and dysesthesia) and that is associated with a human T-cell lymphotropic virus type 1 (HTLV-1) infection.

ID

http://www.orpha.net/ORDO/Orphanet_289326

alternative_term

HTLV-1-associated myelopathy/tropical spastic paraparesis

TSP

HAM/TSP

Human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis

Human T-lymphotropic virus type-1-associated myelopathy/tropical spastic paraparesis

definition

Tropical spastic paraparesis is a chronic systemic immune-mediated inflammatory myeloneuropathy, more frequently reported in women than in men, that usually presents in adulthood with slowly progressive spastic paraparesis of the lower limbs, bladder and bowel dysfunction, and sensory disturbances in the lower extremities (e.g. paresthesia and dysesthesia) and that is associated with a human T-cell lymphotropic virus type 1 (HTLV-1) infection.

definition_citation

Orphanet

expertlink

https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=en&Expert=289326

has_age_of_onset

Adult

has_inheritance

Not applicable

hasDbXref

UMLS:C0030481

ICD-10:G04.1

MedDRA:10044696

MeSH:D015493

OMIM:159580

ICD-11:8A45.00

label

Tropical spastic paraparesis

notation

ORPHA:289326

part_of

http://www.orpha.net/ORDO/Orphanet_98010

http://www.orpha.net/ORDO/Orphanet_163585

prefixIRI

ORDO:Orphanet_289326

prefLabel

Tropical spastic paraparesis

present_in

Worldwide AND has_point_prevalence_range : Unknown

treeView

http://www.orpha.net/ORDO/Orphanet_98010

http://www.orpha.net/ORDO/Orphanet_163585

subClassOf

http://www.orpha.net/ORDO/Orphanet_377788

http://www.orpha.net/ORDO/Orphanet_557493

Delete Subject Author Type Created
No notes to display