Orphanet Rare Disease Ontology

Last uploaded: July 3, 2024
Preferred Name

Diffuse astrocytoma

Synonyms
Definitions

A rare low-grade astrocytoma characterized by a high degree of cellular differentiation, slow growth, and diffuse infiltration of adjacent brain structures, and corresponding to WHO grade II. The tumor typically affects young adults and has an intrinsic tendency for progression to high-grade glioma. Histological variants are fibrillary, gemistocytic, and protoplasmic astrocytoma. Patients most commonly present with seizures, but also with other neurological or neuropsychological abnormalities, depending on the location.

ID

http://www.orpha.net/ORDO/Orphanet_251595

definition

A rare low-grade astrocytoma characterized by a high degree of cellular differentiation, slow growth, and diffuse infiltration of adjacent brain structures, and corresponding to WHO grade II. The tumor typically affects young adults and has an intrinsic tendency for progression to high-grade glioma. Histological variants are fibrillary, gemistocytic, and protoplasmic astrocytoma. Patients most commonly present with seizures, but also with other neurological or neuropsychological abnormalities, depending on the location.

definition_citation

Orphanet

expertlink

https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=en&Expert=251595

has_age_of_onset

Adolescent

Adult

Childhood

hasDbXref

UMLS:C0280785

ICD-11:2A00.0Y

ICD-11:XH2HK4

ICD-11:XH8W32

ICD-11:XH6UY7

ICD-11:XH2C49

ICD-10:C71.9

label

Diffuse astrocytoma

notation

ORPHA:251595

part_of

http://www.orpha.net/ORDO/Orphanet_251592

prefixIRI

ORDO:Orphanet_251595

prefLabel

Diffuse astrocytoma

present_in

United States AND has_annual_incidence_average_value : 0.48 AND has_annual_incidence_range : 1-9 / 1 000 000

treeView

http://www.orpha.net/ORDO/Orphanet_251592

subClassOf

http://www.orpha.net/ORDO/Orphanet_377788

http://www.orpha.net/ORDO/Orphanet_557493

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