Orphanet Rare Disease Ontology

Last uploaded: July 3, 2024
Preferred Name

Anaplastic astrocytoma
Synonyms
Definitions

A rare, high-grade, malignant glial tumor, histologically characterized by abundance of pleomorphic astrocytes and multiple mitotic figures, often associated with diffuse infiltration of the surrounding tissue, considerable edema and mass effect and involvement of the contralateral brain. Depending on the primary localization of the tumor, patients can present with signs of raised intracranial pressure (headache, vomiting, papilledema), seizures, progressive neurological deficits, and/or behavioral changes. The tumor is most commonly localized in the frontal and temporal lobes, brain stem and spinal cord.

ID

http://www.orpha.net/ORDO/Orphanet_251589

definition

A rare, high-grade, malignant glial tumor, histologically characterized by abundance of pleomorphic astrocytes and multiple mitotic figures, often associated with diffuse infiltration of the surrounding tissue, considerable edema and mass effect and involvement of the contralateral brain. Depending on the primary localization of the tumor, patients can present with signs of raised intracranial pressure (headache, vomiting, papilledema), seizures, progressive neurological deficits, and/or behavioral changes. The tumor is most commonly localized in the frontal and temporal lobes, brain stem and spinal cord.

definition_citation

Orphanet

expertlink

https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=en&Expert=251589

has_age_of_onset

Adult

has_inheritance

Not applicable

hasDbXref

UMLS:C0334579

ICD-11:XH96C7

ICD-11:XH39Z7

ICD-11:2A00.0Y

MedDRA:10002224

ICD-10:C71.9

ICD-11:XH7HQ6

label

Anaplastic astrocytoma

notation

ORPHA:251589

part_of

http://www.orpha.net/ORDO/Orphanet_251561

prefixIRI

ORDO:Orphanet_251589

prefLabel

Anaplastic astrocytoma

present_in

United States AND has_annual_incidence_average_value : 0.4 AND has_annual_incidence_range : 1-9 / 1 000 000

treeView

http://www.orpha.net/ORDO/Orphanet_251561

subClassOf

http://www.orpha.net/ORDO/Orphanet_377788

http://www.orpha.net/ORDO/Orphanet_557493

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