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Bilingual Ontology of Alzheimer's Disease and Related Diseases
| Preferred Name | Disulfiram | |
| Synonyms |
TTD Teturamin Tetraethylthioperoxydicarbonic Diamide Tetraethylthioperoxydicarbonic Diamide, ((H2N)C(S))2S2 Tetraethylthiuram Disulfide Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetraethyl- Bis(diethylthiocarbamoyl) Disulfide |
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| Definitions |
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase. (source : MSH) |
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| ID |
http://doe-generated-ontology.com/OntoAD#C0012772 |
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| altLabel |
TTD Teturamin Tetraethylthioperoxydicarbonic Diamide Tetraethylthioperoxydicarbonic Diamide, ((H2N)C(S))2S2 Tetraethylthiuram Disulfide Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetraethyl- Bis(diethylthiocarbamoyl) Disulfide
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| contraindicated_drug |
http://doe-generated-ontology.com/OntoAD#C0013182 http://doe-generated-ontology.com/OntoAD#C0027051 |
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| definition |
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase. (source : MSH)
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| has_contraindicating_class | ||
| hiddenLabel |
Disulfiram
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| induces |
http://doe-generated-ontology.com/OntoAD#C0020649 http://doe-generated-ontology.com/OntoAD#C0018681 |
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| may_prevent | ||
| prefixIRI |
OntoAD:C0012772
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| prefLabel |
Disulfiram
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| subClassOf |
http://doe-generated-ontology.com/OntoAD#C1627760 http://doe-generated-ontology.com/OntoAD#C0014432 http://doe-generated-ontology.com/OntoAD#C0001947 http://doe-generated-ontology.com/OntoAD#C0596326 |
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