Rash, edema, and arthralgia may occur during crisis [MISCELLANEOUS] Recurrent febrile crises with lymphadenopathy, hepatosplenomegaly, vomiting, and diarrhea [MISCELLANEOUS] Febrile crises decrease with age, with ataxia becoming the predominant symptom (in some patients) [MISCELLANEOUS] Caused by mutation in the mevalonate kinase gene (MVK, 251170.0001) [MOLECULAR BASIS] Allelic to hyperimmunoglobulinemia D syndrome (HIDS, 260920) [MISCELLANEOUS] Onset of crises in early childhood [MISCELLANEOUS]
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