Preferred Name | topiramate | |
Synonyms |
TPM CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate InChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1 Topamax InChIKey=KJADKKWYZYXHBB-XBWDGYHZSA-N 2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate tipiramate C12H21NO8S topiramato RWJ-17021 tipiramato topiramatum topiramate McN-4853 Topiramate |
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Definitions |
A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine. |
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ID |
http://purl.obolibrary.org/obo/CHEBI_63631 |
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database_cross_reference |
KEGG COMPOUND:C07502 Wikipedia:Topiramate ChemIDplus:97240-79-4 CiteXplore:22233396 Reaxys:5988957 DrugBank:DB00273 CiteXplore:22249827 KEGG COMPOUND:97240-79-4 KEGG DRUG:D00537 Patent:US4513006 |
|
definition |
A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine. |
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has_alternative_id |
CHEBI:9633 |
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has_exact_synonym |
Topiramate |
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has_related_synonym |
TPM CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate InChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1 Topamax InChIKey=KJADKKWYZYXHBB-XBWDGYHZSA-N 2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate tipiramate C12H21NO8S topiramato RWJ-17021 tipiramato topiramatum topiramate McN-4853 |
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has_RxCUI |
38404 |
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id |
CHEBI:63631 |
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imported from | ||
label |
topiramate |
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notation |
CHEBI:63631 |
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prefLabel |
topiramate |
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subClassOf |
http://purl.obolibrary.org/obo/CHEBI_48199 |