loading...| Preferred Name | Sotalol | |
| Synonyms |
C12H20N2O3S beta-cardone InChIKey=ZBMZVLHSJCTVON-UHFFFAOYSA-N sotalol InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3 sotalolum 4'-(1-hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1 N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide Sotalol |
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| Definitions |
A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is sustituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_63622 |
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| bearer of at some time | ||
| database_cross_reference |
KEGG COMPOUND:C07309 Reaxys:2380820 CiteXplore:21553267 KEGG DRUG:D08525 CiteXplore:20562595 KEGG COMPOUND:3930-20-9 DrugBank:DB00489 CiteXplore:21854895 ChemIDplus:3930-20-9 Wikipedia:Sotalol |
|
| definition |
A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is sustituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias. |
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| has_alternative_id |
CHEBI:9206 |
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| has_exact_synonym |
N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide Sotalol |
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| has_related_synonym |
C12H20N2O3S beta-cardone InChIKey=ZBMZVLHSJCTVON-UHFFFAOYSA-N sotalol InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3 sotalolum 4'-(1-hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1 |
|
| has_RxCUI |
9947 |
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| id |
CHEBI:63622 |
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| imported from | ||
| label |
sotalol Sotalol |
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| notation |
CHEBI:63622 |
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| prefLabel |
Sotalol |
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| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_35358 http://purl.obolibrary.org/obo/CHEBI_50995 |