cerebral amyloid angiopathy

Cerebral amyloid angiopathy (CAA), also known as congophilic angiopathy, is a form of angiopathy in which amyloid deposits form in the walls of the blood vessels of the central nervous system. The amyloid material is only found in the brain and as such the disease is not related to other forms of amyloidosis. A heterogeneous group of sporadic or familial disorders characterized by AMYLOID deposits in the walls of small and medium sized blood vessels of CEREBRAL CORTEX and MENINGES. Clinical features include multiple, small lobar CEREBRAL HEMORRHAGE; cerebral ischemia ( BRAIN ISCHEMIA); and CEREBRAL INFARCTION. Cerebral amyloid angiopathy is unrelated to generalizedAMYLOIDOSIS. Amyloidogenic peptides in this condition are nearly always the same ones found in ALZHEIMER DISEASE.

http://purl.obolibrary.org/obo/ND_0000188

congophilic angiopathy

amyloid angiopathy

CAA

Alexander P. Cox

http://en.wikipedia.org/wiki/Cerebral_amyloid_angiopathy

Kumar: Robbins and Cotran: Pathologic Basis of Disease, 7th ed., 2005

cerebral amyloid angiopathy

ND:0000188

cerebral amyloid angiopathy

Cerebral amyloid angiopathy (CAA), also known as congophilic angiopathy, is a form of angiopathy in which amyloid deposits form in the walls of the blood vessels of the central nervous system. The amyloid material is only found in the brain and as such the disease is not related to other forms of amyloidosis.

A heterogeneous group of sporadic or familial disorders characterized by AMYLOID deposits in the walls of small and medium sized blood vessels of CEREBRAL CORTEX and MENINGES. Clinical features include multiple, small lobar CEREBRAL HEMORRHAGE; cerebral ischemia ( BRAIN ISCHEMIA); and CEREBRAL INFARCTION. Cerebral amyloid angiopathy is unrelated to generalizedAMYLOIDOSIS. Amyloidogenic peptides in this condition are nearly always the same ones found in ALZHEIMER DISEASE.

http://purl.obolibrary.org/obo/ND_0000186