Preferred Name

Tonic-Clonic Epilepsy

Synonyms

Grand Mal Convulsions

Tonic-Clonic Seizure Disorder

Grand Mal Seizure Disorder

Grand Mal Convulsions Epilepsy

Tonic-Clonic Convulsions

Major Epilepsy

Major Motor Seizure Disorder

Grand Mal Seizures Disorder

Tonic-Clonic Convulsion Disorder

Tonic-Clonic Seizure Syndrome

Tonic-Clonic Convulsion Syndrome

Definitions

A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process) (MeSH).

ID

http://uri.neuinfo.org/nif/nifstd/birnlex_12743

alternative label

Grand Mal Convulsions

Tonic-Clonic Seizure Disorder

Grand Mal Seizure Disorder

Grand Mal Convulsions Epilepsy

Tonic-Clonic Convulsions

Major Epilepsy

Major Motor Seizure Disorder

Grand Mal Seizures Disorder

Tonic-Clonic Convulsion Disorder

Tonic-Clonic Seizure Syndrome

Tonic-Clonic Convulsion Syndrome

createdDate

2007-10-08

definingCitation

Adams et al., Principles of Neurology, 6th ed, p329

definition

A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process) (MeSH).

editorial note

http://uri.neuinfo.org/nif/nifstd/readable/uncurated

externalSourceId

D004830

_8.3_5.2.1

hasBirnlexCurator

http://uri.neuinfo.org/nif/nifstd/readable/Bill_Bug

hasCurationStatus

http://uri.neuinfo.org/nif/nifstd/readable/uncurated

hasDefinitionSource

http://uri.neuinfo.org/nif/nifstd/readable/MeSH_defSource

hasExternalSource

http://uri.neuinfo.org/nif/nifstd/readable/MeSH

label

Tonic-Clonic Epilepsy

MeshUid

D004830

modifiedDate

2007-10-08

nifID

_8.3_5.2.1

note

A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process) (MeSH).

http://uri.neuinfo.org/nif/nifstd/readable/uncurated

preferred label

Tonic-Clonic Epilepsy

putativeClassExtension

Cryptogenic Tonic-Clonic Epilepsy

Symptomatic Tonic-Clonic Epilepsy

Resource Identifier

D004830

_8.3_5.2.1

synonym

Grand Mal Convulsions

Tonic-Clonic Seizure Disorder

Grand Mal Seizure Disorder

Grand Mal Convulsions Epilepsy

Tonic-Clonic Convulsions

Major Epilepsy

Major Motor Seizure Disorder

Grand Mal Seizures Disorder

Tonic-Clonic Convulsion Disorder

Tonic-Clonic Seizure Syndrome

Tonic-Clonic Convulsion Syndrome

usageNote

MeSH includes implied subtypes

subClassOf

http://purl.obolibrary.org/obo/DOID_1827

http://purl.obolibrary.org/obo/DOID_0050705

http://uri.neuinfo.org/nif/nifstd/birnlex_12737

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