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Neuroscience Information Framework (NIF) Standard Ontology
| Preferred Name | integrin alpha-M | |
| Synonyms |
CD11B CR3A CR-3 alpha chain CD11 antigen-like family member B neutrophil adherence receptor cell surface glycoprotein MAC-1 subunit alpha leukocyte adhesion receptor MO1 CD11b ITGAM |
|
| Definitions |
An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. An integrin alpha with A domain that is a translation product of the ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. Category=gene. Requested by=CL. Category=gene. |
|
| ID |
http://purl.obolibrary.org/obo/PR_000001012 |
|
| comment |
Category=gene. Requested by=CL. Category=gene.
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|
| alternative label |
CD11B CR3A CR-3 alpha chain CD11 antigen-like family member B neutrophil adherence receptor cell surface glycoprotein MAC-1 subunit alpha leukocyte adhesion receptor MO1 CD11b ITGAM
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| crossSpeciesExactMatch | ||
| database_cross_reference |
IUPHARobj:2452
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|
| definition |
An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. An integrin alpha with A domain that is a translation product of the ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. Category=gene. Requested by=CL. Category=gene.
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|
| has exact synonym |
CR-3 alpha chain CD11 antigen-like family member B neutrophil adherence receptor cell surface glycoprotein MAC-1 subunit alpha leukocyte adhesion receptor MO1 CD11b ITGAM
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|
| has_obo_namespace |
protein
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|
| has_related_synonym |
CD11B CR3A
|
|
| id |
PR:000001012
|
|
| label |
integrin alpha-M
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|
| notation |
PR:000001012
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|
| note |
An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. An integrin alpha with A domain that is a translation product of the ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. Category=gene. Requested by=CL. Category=gene.
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|
| preferred label |
integrin alpha-M
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|
| prefLabel |
integrin alpha-M
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| subClassOf |
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