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Neuroscience Information Framework (NIF) Dysfunction Ontlogy
Last uploaded:
April 11, 2018
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| Preferred Name | Multiple System Atrophy | |
| Synonyms |
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| Definitions |
A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord (MeSH). |
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| ID |
http://uri.neuinfo.org/nif/nifstd/birnlex_12573 |
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| createdDate |
2007-10-05
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| definingCitation |
Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92
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| definingCitationURI | ||
| definition |
A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord (MeSH).
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| editorial note | ||
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| label |
Multiple System Atrophy
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| MeshUid |
D019578
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| modifiedDate |
2007-10-05
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| nifID |
_8.3_2.11
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| note |
A specific neurodegenerative syndrome complex; not for atrophy in other systems (BB: 2007-10-05) A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord (MeSH).
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| preferred label |
Multiple System Atrophy
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| scope note |
A specific neurodegenerative syndrome complex; not for atrophy in other systems (BB: 2007-10-05)
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| synonym |
Multisystemic Atrophy Multiple System Atrophy Syndrome Multisystem Atrophy
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