Next Generation Biobanking Ontology

Last uploaded: May 8, 2024
Preferred Name

dendritic cell

Synonyms
Definitions

Large, stellate fibroblast found along the network of collagen fibers of the reticulum of the spleen; synthesize the matrix components of the reticulum. A special type of cell that is a key regulator of the immune system, acting as a professional antigen-presenting cell, APC, capable of activating naive T cells and stimulating the growth and differentiation of B cells. Dendritic cells are found, for example, in the lymph nodes and spleen. As an APC, a dendritic cell can retain antigen for long periods on its surface, present the antigen to a T or B cell and so influence their behavior. A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.

ID

http://purl.obolibrary.org/obo/CL_0000451

label

dendritic cell

NCI_Thesaurus_definition_citation

NCIt:C12583

prefixIRI

CL:0000451

prefLabel

dendritic cell

SNOMEDCT_definition_citation

SNOMEDCT:37510001

SNOMEDCT:24333000

SNOMEDCT:127942009

term editor

Tomasz Adamusiak

James Malone

textual definition

Large, stellate fibroblast found along the network of collagen fibers of the reticulum of the spleen; synthesize the matrix components of the reticulum.

A special type of cell that is a key regulator of the immune system, acting as a professional antigen-presenting cell, APC, capable of activating naive T cells and stimulating the growth and differentiation of B cells. Dendritic cells are found, for example, in the lymph nodes and spleen. As an APC, a dendritic cell can retain antigen for long periods on its surface, present the antigen to a T or B cell and so influence their behavior.

A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.

subClassOf

http://www.ebi.ac.uk/efo/EFO_0000324

http://purl.obolibrary.org/obo/CL_0000738

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http://purl.obolibrary.org/obo/CL_0000451 CL SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 UBERON SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 MONDO SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 OBA SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 EFO SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 OBI SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 DOID SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 HRA SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 MAXO SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 PDRO SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 CLO SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 FOVT SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 HOIP SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 CHEAR SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 ONE SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 OBI_BCGO SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 EGO SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 PCL SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 NIFDYS SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 BERO SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 HHEAR SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 TXPO SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 UPHENO SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 OBI_IEE SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 KTAO SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 IDOMAL SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 CCF SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 IDODEN SAME_URI
http://purl.obolibrary.org/obo/CL_0000451 CL LOOM
http://purl.obolibrary.org/obo/CL_0000451 UBERON LOOM
http://purl.obolibrary.org/obo/CL_0000451 OBA LOOM
http://purl.obolibrary.org/obo/CL_0000451 EFO LOOM
http://purl.obolibrary.org/obo/CL_0000451 OBI LOOM
http://purl.obolibrary.org/obo/CL_0000451 DOID LOOM
http://purl.obolibrary.org/obo/CL_0000451 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CL_0000451 MAXO LOOM
http://purl.org/obo/owlapi/fma#FMA_83036 BIOMODELS LOOM
http://scai.fraunhofer.de/MSOntology#Dendritic_Cell MSO LOOM
http://purl.obolibrary.org/obo/NCIT_C12583 BERO LOOM
http://purl.bioontology.org/ontology/CSP/0432-1437 CRISP LOOM
http://purl.obolibrary.org/obo/CL_0000451 PDRO LOOM
http://purl.obolibrary.org/obo/CL_0000451 CLO LOOM
http://purl.obolibrary.org/obo/CL_0000451 FOVT LOOM
http://purl.obolibrary.org/obo/CL_0000451 HOIP LOOM
http://purl.obolibrary.org/obo/CL_0000451 CHEAR LOOM
http://purl.obolibrary.org/obo/CL_0000451 ONE LOOM
http://purl.obolibrary.org/obo/CL_0000451 OBI_BCGO LOOM
http://purl.obolibrary.org/obo/CL_0000451 EGO LOOM
http://purl.obolibrary.org/obo/CL_0000451 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CL_0000451 PCL LOOM
http://purl.obolibrary.org/obo/CL_0000451 NIFDYS LOOM
http://purl.obolibrary.org/obo/CL_0000451 HHEAR LOOM
http://purl.obolibrary.org/obo/CL_0000451 TXPO LOOM
http://purl.obolibrary.org/obo/CL_0000451 UPHENO LOOM
http://purl.obolibrary.org/obo/CL_0000451 OBI_IEE LOOM
http://purl.obolibrary.org/obo/CL_0000451 NIFSTD LOOM
http://purl.obolibrary.org/obo/CL_0000451 KTAO LOOM
http://purl.obolibrary.org/obo/CL_0000451 IDOMAL LOOM
http://purl.obolibrary.org/obo/CL_0000451 CCF LOOM
http://purl.obolibrary.org/obo/CL_0000451 IDODEN LOOM
http://purl.org/obo/owl/CL#CL_0000451 BIOMODELS LOOM
http://purl.jp/bio/4/id/200906084743878154 IOBC LOOM
http://purl.obolibrary.org/obo/BTO_0002042 DTO LOOM
http://purl.obolibrary.org/obo/BTO_0002042 BTO LOOM
http://purl.bioontology.org/ontology/SNMI/T-01151 SNMI LOOM
http://www.projecthalo.com/aura#Dendritic-Cell AURA LOOM
http://purl.obolibrary.org/obo/LMMA_00150 LUNGMAP_M_CELL LOOM
http://purl.obolibrary.org/obo/LMMA_00150 LUNGMAP-MOUSE LOOM
http://purl.obolibrary.org/obo/ZFA_0009209 ZFA LOOM
http://purl.obolibrary.org/obo/ZFA_0009209 UPHENO LOOM
http://purl.obolibrary.org/obo/ZFA_0009209 ZP LOOM
http://purl.obolibrary.org/obo/LMHA_00150 LUNGMAP_H_CELL LOOM
http://purl.obolibrary.org/obo/LMHA_00150 LUNGMAP-HUMAN LOOM
http://purl.obolibrary.org/obo/TAO_0009209 TAO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12583 NCIT LOOM