loading...| Preferred Name | Multiple Endocrine Neoplasia Type 2b [Disease/Finding] | |
| Synonyms |
Neoplasia, Multiple Endocrine Type 2b Multiple Endocrine Neoplasms Type 2b MEN 3 Multiple Endocrine Neoplasia Type 2b MEN 2b MEN IIb Wagenmann-Froboese Syndrome Multiple Endocrine Neoplasia, Type 2b MEN2b MEA 2b MEN III Neuromata, Mucosal, With Endocrine Tumors MEA IIb Neoplasms, Multiple Endocrine Type 2b Multiple Endocrine Neoplasia, Type IIb Mucosal Neuroma Syndrome |
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| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000003863 |
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| altLabel |
Neoplasia, Multiple Endocrine Type 2b Multiple Endocrine Neoplasms Type 2b MEN 3 Multiple Endocrine Neoplasia Type 2b MEN 2b MEN IIb Wagenmann-Froboese Syndrome Multiple Endocrine Neoplasia, Type 2b MEN2b MEA 2b MEN III Neuromata, Mucosal, With Endocrine Tumors MEA IIb Neoplasms, Multiple Endocrine Type 2b Multiple Endocrine Neoplasia, Type IIb Mucosal Neuroma Syndrome |
|
| cui |
C0025269 |
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| MESH DEFINITION |
Similar to MEN2A, it is also caused by mutations of the MEN2 gene, also known as the RET proto-oncogene. Its clinical symptoms include medullary carcinoma (CARCINOMA, MEDULLARY) of THYROID GLAND and PHEOCHROMOCYTOMA of ADRENAL MEDULLA (50%). Unlike MEN2a, MEN2b does not involve PARATHYROID NEOPLASMS. It can be distinguished from MEN2A by its neural abnormalities such as mucosal NEUROMAS on EYELIDS; LIP; and TONGUE, and ganglioneuromatosis of GASTROINTESTINAL TRACT leading to MEGACOLON. It is an autosomal dominant inherited disease. |
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| MESH DUI |
D018814 |
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| MeSH name |
Multiple Endocrine Neoplasia Type 2b |
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| MESH UI |
M0028167 |
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| NDFRT kind |
DISEASE_KIND |
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| notation |
N0000003863 |
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| NUI |
N0000003863 |
|
| prefLabel |
Multiple Endocrine Neoplasia Type 2b [Disease/Finding] |
|
| SNOMED CID |
61530001 |
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| tui |
T191 |
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| subClassOf |