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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Paraben | |
| Synonyms |
Paraben Derivatives para-Hydroxybenzoic Acid Ester Paraben Parabens |
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| Definitions |
An alkyl ester of p-hydroxybenzoic acid (PHBA) that is used most often as a preservative in various personal care products. Parabens are active against a broad spectrum of microorganisms and exert their activity by disrupting the integrity of the cell membrane, causing leakage of intracellular proteins and interference with membrane transport processes, by inhibiting synthesis of DNA and RNA or by inhibiting the activity of certain enzymes, such as ATPases and phosphotransferases. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C92608 |
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| code |
C92608
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| DEFINITION |
An alkyl ester of p-hydroxybenzoic acid (PHBA) that is used most often as a preservative in various personal care products. Parabens are active against a broad spectrum of microorganisms and exert their activity by disrupting the integrity of the cell membrane, causing leakage of intracellular proteins and interference with membrane transport processes, by inhibiting synthesis of DNA and RNA or by inhibiting the activity of certain enzymes, such as ATPases and phosphotransferases.
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| FULL_SYN |
Paraben Derivatives para-Hydroxybenzoic Acid Ester Paraben Parabens
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|
| label |
Paraben
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| Preferred_Name |
Paraben
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| prefixIRI |
Thesaurus:C92608
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| Semantic_Type |
Chemical Viewed Functionally
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| UMLS_CUI |
C0030398
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| subClassOf |
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