National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

L-Tyrosine
Synonyms

(S)-2-Amino-3-(4-hydroxy-phenyl)propanoic acid

TYROSINE, (L)

L-Phenylalanine, 4-hydroxy-

L-Tyrosine

TYR

TYROSINE

Tyr

Tyrosine

Definitions

The levorotatory isomer of the aromatic amino acid tyrosine. L-tyrosine is a naturally occurring tyrosine and is synthesized in vivo from L-phenylalanine. It is considered a non-essential amino acid; however, in patients with phenylketonuria who lack phenylalanine hydroxylase and cannot convert phenylalanine into tyrosine, it is considered an essential nutrient. In vivo, tyrosine plays a role in protein synthesis and serves as a precursor for the synthesis of catecholamines, thyroxine, and melanin.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C915

ALT_DEFINITION

Amino acid with side chain -CH2-C6H4OH.

CAS_Registry

60-18-4

CHEBI_ID

CHEBI:17895

Chemical_Formula

C9H11NO3

code

C915

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CRCH

CTRP

FDA

DEFINITION

The levorotatory isomer of the aromatic amino acid tyrosine. L-tyrosine is a naturally occurring tyrosine and is synthesized in vivo from L-phenylalanine. It is considered a non-essential amino acid; however, in patients with phenylketonuria who lack phenylalanine hydroxylase and cannot convert phenylalanine into tyrosine, it is considered an essential nutrient. In vivo, tyrosine plays a role in protein synthesis and serves as a precursor for the synthesis of catecholamines, thyroxine, and melanin.

Display_Name

L-Tyrosine

FDA_UNII_Code

42HK56048U

FULL_SYN

(S)-2-Amino-3-(4-hydroxy-phenyl)propanoic acid

TYROSINE, (L)

L-Phenylalanine, 4-hydroxy-

L-Tyrosine

TYR

TYROSINE

Tyr

Tyrosine

INFOODS

TYR_G

label

L-Tyrosine

Legacy Concept Name

Tyrosine

NSC Number

9973

Preferred_Name

L-Tyrosine

prefixIRI

Thesaurus:C915

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0041485

Unit

g

USDA_ID

509

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68442

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29596

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_17895 UBERON LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 PCL LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 OBA LOOM
http://purl.obolibrary.org/obo/OGCO_00000098 OGCO LOOM
http://purl.bioontology.org/ontology/RCD/XaDdc RCD LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 UBERON LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 FOBI LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 CIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 ONSTR LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 ZP LOOM
http://purl.obolibrary.org/obo/CHEBI_17895 OBA LOOM
http://purl.obolibrary.org/obo/UPa_UPC00082 UPA LOOM
http://purl.obolibrary.org/obo/NCIT_C915 BERO LOOM
http://purl.jp/bio/10/gmo/GMO_001808 GMO LOOM
http://www.drugbank.ca/drugs/DB00135 FTC LOOM
http://purl.obolibrary.org/obo/IMR_0200240 HOIP LOOM
http://purl.obolibrary.org/obo/IMR_0200240 TXPO LOOM