loading...| Preferred Name | Tetracycline | |
| Synonyms |
4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide TETRACYCLINE tetracycline Tetracycline TCN |
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| Definitions |
A broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens. In bacteria, tetracycline binds to the 30S ribosomal subunit, interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C865 |
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| ALT_DEFINITION |
A drug used to treat bacterial infections. It stops the growth of bacteria by keeping them from making proteins. Tetracycline also binds to new bone tissue and is being studied as a way to detect bone growth. Tetracycline is a type of antibiotic and a type of bone-labeling agent. |
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| CAS_Registry |
60-54-8 |
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| CHEBI_ID |
CHEBI:27902 |
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| Chemical_Formula |
C22H24N2O8 |
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| code |
C865 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA HemOnc |
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| DEFINITION |
A broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens. In bacteria, tetracycline binds to the 30S ribosomal subunit, interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. |
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| FDA_UNII_Code |
F8VB5M810T |
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| FULL_SYN |
4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide TETRACYCLINE tetracycline Tetracycline TCN |
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| Has_Salt_Form | ||
| label |
Tetracycline |
|
| Legacy Concept Name |
Tetracycline |
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| NSC Number |
108579 |
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| Preferred_Name |
Tetracycline |
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| prefixIRI |
Thesaurus:C865 |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic |
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| UMLS_CUI |
C0039644 |
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| subClassOf |