National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

African Trypanosomiasis
Synonyms

African Trypanosomiasis

Sleeping Sickness

Definitions

A parasitic disorder caused by protozoa of the Trypanosoma brucei species. It is transmitted by flies and is endemic in various regions of Sub-Saharan Africa. Signs and symptoms include fever, joint pain, headache, and significant swelling of the lymph nodes. If left untreated, the parasitic infection causes anemia, heart, kidney, and endocrine failure, and neurologic damage. Subsequently patients develop confusion, disruption of the sleep cycle, and mental deterioration. The infection may lead to coma and death.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84541

ALT_DEFINITION

A protozoan infection that is caused by Trypanosoma brucei, which is transmitted by tsetse flies; it is characterized by fever, joint pain, headache, and lymphadenopathy, and it may progress to multi-organ involvement.

code

C84541

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128453

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158520

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158035

Contributing_Source

CPTAC

NICHD

DEFINITION

A parasitic disorder caused by protozoa of the Trypanosoma brucei species. It is transmitted by flies and is endemic in various regions of Sub-Saharan Africa. Signs and symptoms include fever, joint pain, headache, and significant swelling of the lymph nodes. If left untreated, the parasitic infection causes anemia, heart, kidney, and endocrine failure, and neurologic damage. Subsequently patients develop confusion, disruption of the sleep cycle, and mental deterioration. The infection may lead to coma and death.

FULL_SYN

African Trypanosomiasis

Sleeping Sickness

label

African Trypanosomiasis

Preferred_Name

African Trypanosomiasis

prefixIRI

Thesaurus:C84541

Semantic_Type

Disease or Syndrome

UMLS_CUI

C0041228

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34953

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