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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Fenfluramine | |
| Synonyms |
1-(meta-Trifluoromethyl-phenyl)-2 Ethylaminopropane 2-Ethylamino-1-(3-trifluoromethylphenyl)propane FENFLURAMINE Fenfluramine 3-(Trifluoromethyl)-N-ethyl-alpha-methylphenethylamine |
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| Definitions |
An amphetamine derivative and a sympathomimetic stimulant with appetite-suppressant property. Fenfluramine, which was part of the Fen-Phen anti-obesity medication, stimulates the release of serotonin from vesicular storage, and modulates serotonin transporter function. Since serotonin regulates mood and appetite, among other functions, increased serotonin level results in a feeling of fullness and loss of appetite. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81418 |
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| CAS_Registry |
458-24-2
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|
| CHEBI_ID |
CHEBI:5000
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|
| Chemical_Formula |
C12H16F3N
|
|
| code |
C81418
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| Concept_In_Subset | ||
| Contributing_Source |
FDA
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|
| DEFINITION |
An amphetamine derivative and a sympathomimetic stimulant with appetite-suppressant property. Fenfluramine, which was part of the Fen-Phen anti-obesity medication, stimulates the release of serotonin from vesicular storage, and modulates serotonin transporter function. Since serotonin regulates mood and appetite, among other functions, increased serotonin level results in a feeling of fullness and loss of appetite.
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|
| FDA_UNII_Code |
2DS058H2CF
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|
| FULL_SYN |
1-(meta-Trifluoromethyl-phenyl)-2 Ethylaminopropane 2-Ethylamino-1-(3-trifluoromethylphenyl)propane FENFLURAMINE Fenfluramine 3-(Trifluoromethyl)-N-ethyl-alpha-methylphenethylamine
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|
| Has_Salt_Form | ||
| label |
Fenfluramine
|
|
| Legacy Concept Name |
Fenfluramine
|
|
| Preferred_Name |
Fenfluramine
|
|
| prefixIRI |
Thesaurus:C81418
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|
| Semantic_Type |
Pharmacologic Substance
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|
| UMLS_CUI |
C0015827
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|
| subClassOf |
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