Link to this page
National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
Jump to:
| Preferred Name | Esketamine | |
| Synonyms |
Ketamine, S- ESKETAMINE Esketamine L-Ketamine |
|
| Definitions |
A cyclohexanone derivative and S-enantiomer of racemic ketamine, with analgesic, anesthetic and antidepressant activities. Although the mechanism of action is not fully understood, upon administration, esketamine targets, non-competitively binds to, and blocks N-methyl D-aspartate (NMDA) receptors. This reduces pain perception, induces sedation, and produce dissociative anesthesia. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81400 |
|
| CAS_Registry |
33643-46-8
|
|
| CHEBI_ID |
CHEBI:60799
|
|
| Chemical_Formula |
C13H16ClNO
|
|
| code |
C81400
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
A cyclohexanone derivative and S-enantiomer of racemic ketamine, with analgesic, anesthetic and antidepressant activities. Although the mechanism of action is not fully understood, upon administration, esketamine targets, non-competitively binds to, and blocks N-methyl D-aspartate (NMDA) receptors. This reduces pain perception, induces sedation, and produce dissociative anesthesia.
|
|
| FDA_UNII_Code |
50LFG02TXD
|
|
| FULL_SYN |
Ketamine, S- ESKETAMINE Esketamine L-Ketamine
|
|
| label |
Esketamine
|
|
| Legacy Concept Name |
Esketamine
|
|
| Preferred_Name |
Esketamine
|
|
| prefixIRI |
Thesaurus:C81400
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C2825616
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping