loading...| Preferred Name |
Fenfluramine Hydrochloride |
|
| Synonyms |
FENFLURAMINE HYDROCHLORIDE Fenfluramine Hydrochloride Fintepla |
|
| Definitions |
The hydrochloride salt of fenfluramine, an amphetamine derivative and a sympathomimetic stimulant with appetite-suppressant properties. Fenfluramine, which was part of the Fen-Phen anti-obesity medication, stimulates the release of serotonin from vesicular storage, and modulates serotonin transporter function. Since serotonin regulates mood and appetite, among other functions, increased serotonin level results in a feeling of fullness and loss of appetite. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75112 |
|
| Accepted_Therapeutic_Use_For |
treatment of seizures associated with Dravet syndrome in patients 2 years of age and older |
|
| CAS_Registry |
404-82-0 |
|
| CHEBI_ID |
CHEBI:59729 |
|
| Chemical_Formula |
C12H16F3N.HCl |
|
| code |
C75112 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The hydrochloride salt of fenfluramine, an amphetamine derivative and a sympathomimetic stimulant with appetite-suppressant properties. Fenfluramine, which was part of the Fen-Phen anti-obesity medication, stimulates the release of serotonin from vesicular storage, and modulates serotonin transporter function. Since serotonin regulates mood and appetite, among other functions, increased serotonin level results in a feeling of fullness and loss of appetite. |
|
| FDA_UNII_Code |
3KC089243P |
|
| FULL_SYN |
FENFLURAMINE HYDROCHLORIDE Fenfluramine Hydrochloride Fintepla |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Fenfluramine Hydrochloride |
|
| Legacy Concept Name |
Fenfluramine_Hydrochloride |
|
| Preferred_Name |
Fenfluramine Hydrochloride |
|
| prefixIRI |
Thesaurus:C75112 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0282179 |
|
| subClassOf |