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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Pipobroman | |
| Synonyms |
Amedel PIPOBROMAN Pipobroman Vercyte |
|
| Definitions |
A piperazine derivative with potential antineoplastic alkyating activity. Although the exact mechanism of action of pipobroman has yet to be fully elucidated, this agent appears to act by alkylating DNA, leading to disruption of DNA replication and eventually cell death. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C750 |
|
| CAS_Registry |
54-91-1
|
|
| Chemical_Formula |
C10H16Br2N2O2
|
|
| code |
C750
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
|
| Contributing_Source |
FDA GDC HemOnc
|
|
| DEFINITION |
A piperazine derivative with potential antineoplastic alkyating activity. Although the exact mechanism of action of pipobroman has yet to be fully elucidated, this agent appears to act by alkylating DNA, leading to disruption of DNA replication and eventually cell death.
|
|
| FDA_UNII_Code |
6Q99RDT97R
|
|
| FULL_SYN |
Amedel PIPOBROMAN Pipobroman Vercyte
|
|
| Is_Value_For_GDC_Property | ||
| label |
Pipobroman
|
|
| Legacy Concept Name |
Pipobroman
|
|
| Maps_To |
Pipobroman
|
|
| NSC Number |
25154
|
|
| Preferred_Name |
Pipobroman
|
|
| prefixIRI |
Thesaurus:C750
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0031965
|
|
| subClassOf |
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