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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Deferiprone | |
| Synonyms |
Deferiprone 4(1H)-Pyridinone, 3-hydroxy-1,2-dimethyl- DEFERIPRONE DN-180-01-AF APO-066 CP20 Ferriprox |
|
| Definitions |
An orally bioavailable bidentate ligand with iron chelating activity. Deferiprone binds to iron in a 3:1 (ligand:iron) molar ratio. By binding to iron, deferiprone is able to remove excess iron from the body. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73030 |
|
| Accepted_Therapeutic_Use_For |
Hemosiderosis
|
|
| CAS_Registry |
30652-11-0
|
|
| Chemical_Formula |
C7H9NO2
|
|
| code |
C73030
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 |
|
| Contributing_Source |
FDA HemOnc
|
|
| DEFINITION |
An orally bioavailable bidentate ligand with iron chelating activity. Deferiprone binds to iron in a 3:1 (ligand:iron) molar ratio. By binding to iron, deferiprone is able to remove excess iron from the body.
|
|
| FDA_UNII_Code |
2BTY8KH53L
|
|
| FULL_SYN |
Deferiprone 4(1H)-Pyridinone, 3-hydroxy-1,2-dimethyl- DEFERIPRONE DN-180-01-AF APO-066 CP20 Ferriprox
|
|
| label |
Deferiprone
|
|
| Legacy Concept Name |
Deferiprone
|
|
| NCI_Drug_Dictionary_ID |
761978
|
|
| PDQ_Closed_Trial_Search_ID |
761978
|
|
| PDQ_Open_Trial_Search_ID |
761978
|
|
| Preferred_Name |
Deferiprone
|
|
| prefixIRI |
Thesaurus:C73030
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0043832
|
|
| subClassOf |
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