National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Chelating Agent
Synonyms

Chelating agent

Metal Chelant

chelating agent

Metal Chelating Agent

Chelating Agent

Metal Chelator

Chelators

Definitions

An inorganic or organic molecule which binds metal ions. Metal chelators are frequently polydentate, indicating that they form multiple bonds with the metal ion, resulting in more stable coordination complexes.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C360

ALT_DEFINITION

Used to sequester ions from solution and to form stable complexes (e.g. sequestering agent). (Pharmaceutical Excipients: A review Shilpa P Chaudhari and Pradeep S Patil Marathwada Mitra Mandal's College of Pharmacy, Thergaon, Pune, Maharashtra, India. USP <1059>)

A chemical compound that binds tightly to metal ions. In medicine, chelating agents are used to remove toxic metals from the body. They are also being studied in the treatment of cancer.

CHEBI_ID

CHEBI:38161

code

C360

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133805

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176676

Contributing_Source

FDA

DEFINITION

An inorganic or organic molecule which binds metal ions. Metal chelators are frequently polydentate, indicating that they form multiple bonds with the metal ion, resulting in more stable coordination complexes.

FULL_SYN

Chelating agent

Metal Chelant

chelating agent

Metal Chelating Agent

Chelating Agent

Metal Chelator

Chelators

label

Chelating Agent

Legacy Concept Name

Metal_Chelator

Chelating_Agent

Preferred_Name

Chelating Agent

prefixIRI

Thesaurus:C360

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C1881795

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1932

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