National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Retinol
Synonyms

3,7-Dimethyl-9-(2,6, 6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

All Trans Retinol

3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-nona-2,4,6,8-tetraen-1-ol

RETINOL

Retinol

retinol

Definitions

The fat soluble vitamin retinol. Vitamin A binds to and activates retinoid receptors (RARs), thereby inducing cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. Vitamin A plays an essential role in many physiologic processes, including proper functioning of the retina, growth and differentiation of target tissues, proper functioning of the reproductive organs, and modulation of immune function.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68302

ALT_DEFINITION

Retinoid with a hydroxyl group. Active form of vitamin A which can be converted to the other usable forms; retinal (an aldehyde) and retinoic acid (a carboxylic acid).

CAS_Registry

11103-57-4

68-26-8

CHEBI_ID

CHEBI:17336

Chemical_Formula

C20H30O

code

C68302

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

Contributing_Source

CRCH

FDA

GDC

DEFINITION

The fat soluble vitamin retinol. Vitamin A binds to and activates retinoid receptors (RARs), thereby inducing cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. Vitamin A plays an essential role in many physiologic processes, including proper functioning of the retina, growth and differentiation of target tissues, proper functioning of the reproductive organs, and modulation of immune function.

FDA_UNII_Code

G2SH0XKK91

FULL_SYN

3,7-Dimethyl-9-(2,6, 6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

All Trans Retinol

3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-nona-2,4,6,8-tetraen-1-ol

RETINOL

Retinol

retinol

INFOODS

RETOL

Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1909

label

Retinol

Legacy Concept Name

Retinol

Maps_To

Retinol

NCI_Drug_Dictionary_ID

39735

PDQ_Closed_Trial_Search_ID

39735

PDQ_Open_Trial_Search_ID

39735

Preferred_Name

Retinol

prefixIRI

Thesaurus:C68302

Semantic_Type

Vitamin

UMLS_CUI

C0087161

Unit

mcg

USDA_ID

322

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68299

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C938

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_50211 OBA LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_0815975f_c4dc_49d1_9e25_418b9f4a07cd STO-DRAFT LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_0815975f_c4dc_49d1_9e25_418b9f4a07cd CVAO LOOM
http://purl.obolibrary.org/obo/NCIT_C68302 BERO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU005041 LOINC LOOM
http://www.co-ode.org/ontologies/galen#Retinol GALEN LOOM
http://purl.jp/bio/4/id/200906068682370335 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0087161 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_50211 FOODON LOOM
http://purl.obolibrary.org/obo/CHEBI_50211 EUPATH LOOM
http://purl.obolibrary.org/obo/CHEBI_50211 OCMR LOOM
http://purl.obolibrary.org/obo/CHEBI_50211 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_50211 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_50211 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_50211 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_50211 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_50211 ONSTR LOOM
http://purl.obolibrary.org/obo/CHEBI_50211 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_50211 ZP LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/82622003 SNOMEDCT LOOM
http://purl.jp/bio/10/gmo/GMO_002325 GMO LOOM
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571347974240596134 ACVD_ONTOLOGY LOOM
http://purl.bioontology.org/ontology/ATC/R01AX02 ATC LOOM
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/445354 HHEAR LOOM
http://stirdf.jst.go.jp/id/200907094094356614 IOBC LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0087161 MEDLINEPLUS LOOM
http://purl.bioontology.org/ontology/ATC/D10AD02 ATC LOOM
http://purl.bioontology.org/ontology/ATC/S01XA02 ATC LOOM
http://purl.bioontology.org/ontology/LNC/LP15274-1 LOINC LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039735 PDQ LOOM