National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Ranitidine Bismuth Citrate

Synonyms

RANITIDINE BISMUTH CITRATE

Ranitidine Bismuth Citrate

N-(2-((5-((Dimethylamino)methyl)furfuryl)thio)ethyl)-N'-methyl-2-nitro-1,1-ethenediamine, compound with bismuth(3(+)) citrate (1:1)

Definitions

A member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversible inhibitor of the action of histamine, released by enterochromaffin-like (ECL) cells, at the histamine H2-receptors on parietal cells in the stomach, thereby inhibiting the normal and meal-stimulated secretion of stomach acid. In addition, other substances that promote acid secretion have a reduced effect on parietal cells when the H2 receptors are blocked.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66505

CAS_Registry

128345-62-0

Chemical_Formula

C13H22N4O3S.C6H5O7.Bi

code

C66505

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversible inhibitor of the action of histamine, released by enterochromaffin-like (ECL) cells, at the histamine H2-receptors on parietal cells in the stomach, thereby inhibiting the normal and meal-stimulated secretion of stomach acid. In addition, other substances that promote acid secretion have a reduced effect on parietal cells when the H2 receptors are blocked.

FDA_UNII_Code

7AJ51I17KG

FULL_SYN

RANITIDINE BISMUTH CITRATE

Ranitidine Bismuth Citrate

N-(2-((5-((Dimethylamino)methyl)furfuryl)thio)ethyl)-N'-methyl-2-nitro-1,1-ethenediamine, compound with bismuth(3(+)) citrate (1:1)

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29412

label

Ranitidine Bismuth Citrate

Legacy Concept Name

Ranitidine_Bismuth_Citrate

Preferred_Name

Ranitidine Bismuth Citrate

prefixIRI

Thesaurus:C66505

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0139919

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29702

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