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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29702
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29702
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|---|---|
| Preferred Name | Histamine-2 Receptor Antagonist |
| Definitions |
Any agent that competitively binds to and blocks the histamine H2 receptors found in the stomach, heart, uterus, on vascular smooth muscle and in the central nervous system (CNS). Of particular clinical relevance is the blockage of H2 receptors found on the parietal cells of the stomach, which prevents gastric acid secretion.
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| Synonyms |
H2 Antagonist
H2 Receptor Antagonist
Histamine-2 Receptor Antagonist
H2 Blockers
H2 Blocker
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Histamine-2 Receptor Antagonist
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|---|---|
| Maps_To |
H2 Blockers
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| Legacy Concept Name |
Histamine-2_Receptor_Antagonist
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| CHEBI_ID |
CHEBI:37961
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| Is_Value_For_GDC_Property | |
| Preferred_Name |
Histamine-2 Receptor Antagonist
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| Semantic_Type |
Chemical Viewed Functionally
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| prefixIRI |
Thesaurus:C29702
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| DEFINITION |
Any agent that competitively binds to and blocks the histamine H2 receptors found in the stomach, heart, uterus, on vascular smooth muscle and in the central nervous system (CNS). Of particular clinical relevance is the blockage of H2 receptors found on the parietal cells of the stomach, which prevents gastric acid secretion.
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| UMLS_CUI |
C0019593
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| code |
C29702
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| subClassOf | |
| type | |
| FULL_SYN |
H2 Antagonist
H2 Receptor Antagonist
Histamine-2 Receptor Antagonist
H2 Blockers
H2 Blocker
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| ALT_DEFINITION |
A pharmaceutical agent that blocks the binding of histamine to the type II histamine receptor, and is often used to decrease gastric acid production and to treat urticaria.
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| Contributing_Source |
GDC
NICHD
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| Concept_In_Subset |
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