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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Phenylephrine | |
| Synonyms |
PHENYLEPHRINE Phenylephrine |
|
| Definitions |
A direct-acting sympathomimetic amine chemically related to adrenaline and ephedrine with potent vasoconstrictor property. Phenylephrine is a post-synaptic alpha-adrenergic receptor agonist that causes vasoconstriction, increases systolic/diastolic pressures, reflex bradycardia, and stroke output. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62067 |
|
| ALT_DEFINITION |
Phenylephrine is a sympathomimetic drug whose primary activity results from stimulation of the alpha receptors of the vasculature, resulting in vasoconstriction while producing comparatively mild direct cardiac effects.
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|
| CAS_Registry |
59-42-7
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|
| CHEBI_ID |
CHEBI:8093
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|
| Chemical_Formula |
C9H13NO2
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|
| code |
C62067
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191406 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191200 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191387 |
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| Contributing_Source |
ACC/AHA FDA
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|
| DEFINITION |
A direct-acting sympathomimetic amine chemically related to adrenaline and ephedrine with potent vasoconstrictor property. Phenylephrine is a post-synaptic alpha-adrenergic receptor agonist that causes vasoconstriction, increases systolic/diastolic pressures, reflex bradycardia, and stroke output.
|
|
| FDA_UNII_Code |
1WS297W6MV
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|
| FULL_SYN |
PHENYLEPHRINE Phenylephrine
|
|
| Has_Salt_Form | ||
| label |
Phenylephrine
|
|
| Legacy Concept Name |
Phenylephrine_Base
|
|
| Preferred_Name |
Phenylephrine
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|
| prefixIRI |
Thesaurus:C62067
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
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|
| UMLS_CUI |
C0031469
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| subClassOf |
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