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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Morphine | |
| Synonyms |
MORPHINE Morphine |
|
| Definitions |
An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. Morphine binds to and activates specific opiate receptors (delta, mu and kappa), each of which are involved in controlling different brain functions. In the central nervous and gastrointestinal systems, this agent exhibits widespread effects including analgesia, anxiolysis, euphoria, sedation, respiratory depression, and gastrointestinal system smooth muscle contraction. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62051 |
|
| CAS_Registry |
57-27-2
|
|
| CHEBI_ID |
CHEBI:17303
|
|
| Chemical_Formula |
C17H19NO3
|
|
| code |
C62051
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186329 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
|
| Contributing_Source |
CTRP FDA PCDC
|
|
| DEFINITION |
An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. Morphine binds to and activates specific opiate receptors (delta, mu and kappa), each of which are involved in controlling different brain functions. In the central nervous and gastrointestinal systems, this agent exhibits widespread effects including analgesia, anxiolysis, euphoria, sedation, respiratory depression, and gastrointestinal system smooth muscle contraction. (NCI04)
|
|
| Display_Name |
Morphine
|
|
| FDA_UNII_Code |
76I7G6D29C
|
|
| FULL_SYN |
MORPHINE Morphine
|
|
| Has_Salt_Form | ||
| label |
Morphine
|
|
| Legacy Concept Name |
Morphine_Base
|
|
| NSC Number |
11411
|
|
| Preferred_Name |
Morphine
|
|
| prefixIRI |
Thesaurus:C62051
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0026549
|
|
| subClassOf |
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