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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Dextromethorphan | |
| Synonyms |
DEXTROMETHORPHAN Dextromethorphan DXM |
|
| Definitions |
A synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62022 |
|
| CAS_Registry |
125-71-3
|
|
| CHEBI_ID |
CHEBI:4470
|
|
| Chemical_Formula |
C18H25NO
|
|
| code |
C62022
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
A synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.
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|
| FDA_UNII_Code |
7355X3ROTS
|
|
| FULL_SYN |
DEXTROMETHORPHAN Dextromethorphan DXM
|
|
| Has_Salt_Form | ||
| label |
Dextromethorphan
|
|
| Legacy Concept Name |
Dextromethorphan_Base
|
|
| Preferred_Name |
Dextromethorphan
|
|
| prefixIRI |
Thesaurus:C62022
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0011816
|
|
| subClassOf |
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