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National Cancer Institute Thesaurus
| Preferred Name | Lidocaine | |
| Synonyms |
2-Diethylamino-2',6'-acetoxylidide Omega-diethylamino-2,6-dimethylacetanilide .omega.-Diethylamino-2,6-dimethylacetanilide 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide 2-(Diethylamino)-2',6'-acetoxylidide Cuivasil Duncaine LIDOCAINE Leostesin Lidocaine Lidothesin Lignocaine Rucaina lidocaine |
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| Definitions |
A synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C614 |
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| Accepted_Therapeutic_Use_For |
Cardiac arrhythmias; Local anesthetic
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|
| ALT_DEFINITION |
A substance used to relieve pain by blocking signals at the nerve endings in skin. It can also be given intravenously to stop heart arrhythmias. It is a type of local anesthetic and antiarrhythmic.
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|
| CAS_Registry |
137-58-6
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|
| CHEBI_ID |
CHEBI:6456
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|
| Chemical_Formula |
C14H22N2O
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|
| code |
C614
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|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159412 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
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| Contributing_Source |
CPTAC CTRP FDA
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|
| DEFINITION |
A synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia.
|
|
| Display_Name |
Lidocaine
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|
| FDA_UNII_Code |
98PI200987
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|
| FULL_SYN |
2-Diethylamino-2',6'-acetoxylidide Omega-diethylamino-2,6-dimethylacetanilide .omega.-Diethylamino-2,6-dimethylacetanilide 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide 2-(Diethylamino)-2',6'-acetoxylidide Cuivasil Duncaine LIDOCAINE Leostesin Lidocaine Lidothesin Lignocaine Rucaina lidocaine
|
|
| Has_Salt_Form | ||
| label |
Lidocaine
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|
| Legacy Concept Name |
Lidocaine
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|
| NCI_Drug_Dictionary_ID |
39607
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|
| NSC Number |
40030
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|
| PDQ_Closed_Trial_Search_ID |
39607
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|
| PDQ_Open_Trial_Search_ID |
39607
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|
| Preferred_Name |
Lidocaine
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|
| prefixIRI |
Thesaurus:C614
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
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|
| UMLS_CUI |
C0023660
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| subClassOf |
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