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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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Preferred Name | Sulfamethoxazole | |
Synonyms |
SULFAMETHOXAZOLE Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)- Sulfisomezole Sulfanilamide, N'-(5-methyl-3-isoxazolyl)- Sulfamethoxazole Gamazole Metoxal Radonil |
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Definitions |
A sulfonamide bacteriostatic antibiotic that is most commonly used in combination with trimethoprim as the drug Bactrim. Sulfamethoxazole competitively inhibits dihydropteroate synthase preventing the formation of dihydropteroic acid, a precursor of folic acid which is required for bacterial growth. |
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ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47737 |
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CAS_Registry |
723-46-6
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CHEBI_ID |
CHEBI:9332
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Chemical_Formula |
C10H11N3O3S
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code |
C47737
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Concept_In_Subset | ||
Contributing_Source |
FDA
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DEFINITION |
A sulfonamide bacteriostatic antibiotic that is most commonly used in combination with trimethoprim as the drug Bactrim. Sulfamethoxazole competitively inhibits dihydropteroate synthase preventing the formation of dihydropteroic acid, a precursor of folic acid which is required for bacterial growth.
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FDA_UNII_Code |
JE42381TNV
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FULL_SYN |
SULFAMETHOXAZOLE Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)- Sulfisomezole Sulfanilamide, N'-(5-methyl-3-isoxazolyl)- Sulfamethoxazole Gamazole Metoxal Radonil
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label |
Sulfamethoxazole
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Legacy Concept Name |
Sulfamethoxazole
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NSC Number |
147832
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Preferred_Name |
Sulfamethoxazole
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prefixIRI |
Thesaurus:C47737
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Semantic_Type |
Pharmacologic Substance
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UMLS_CUI |
C0038689
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subClassOf |
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