National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Methamphetamine Hydrochloride
Synonyms

Methamphetamine Hydrochloride

Benzeneethanamine, N,alpha-dimethyl-, Hydrochloride(9CI)

N,alpha-Dimethylphenethylamine Hydrochloride

d-N-Methyl-beta-phenylisopropylamine Hydrochloride

METHAMPHETAMINE HYDROCHLORIDE

N-methyl-1-phenyl-propan-2-amine

Desoxyn

Definitions

The hydrochloride salt form of methamphetamine, an amphetamine and sympathomimetic amine with CNS stimulating properties. Methamphetamine hydrochloride acts by facilitating the release of catecholamines, particularly noradrenaline and dopamine, from nerve terminals in the brain and inhibits their uptake. This leads to an increase in synaptic concentration of these neurotransmitters and results in an increase of motor activity, causes euphoria, mental alertness and excitement and suppresses appetite. Methamphetamine hydrochloride causes dependence and may cause an increase in heart rate and blood pressure.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47609

CAS_Registry

51-57-0

CHEBI_ID

CHEBI:35340

Chemical_Formula

C10H15N.HCl

code

C47609

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt form of methamphetamine, an amphetamine and sympathomimetic amine with CNS stimulating properties. Methamphetamine hydrochloride acts by facilitating the release of catecholamines, particularly noradrenaline and dopamine, from nerve terminals in the brain and inhibits their uptake. This leads to an increase in synaptic concentration of these neurotransmitters and results in an increase of motor activity, causes euphoria, mental alertness and excitement and suppresses appetite. Methamphetamine hydrochloride causes dependence and may cause an increase in heart rate and blood pressure.

FDA_UNII_Code

997F43Z9CV

FULL_SYN

Methamphetamine Hydrochloride

Benzeneethanamine, N,alpha-dimethyl-, Hydrochloride(9CI)

N,alpha-Dimethylphenethylamine Hydrochloride

d-N-Methyl-beta-phenylisopropylamine Hydrochloride

METHAMPHETAMINE HYDROCHLORIDE

N-methyl-1-phenyl-propan-2-amine

Desoxyn

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61840

label

Methamphetamine Hydrochloride

Legacy Concept Name

Methamphetamine_Hydrochloride

NSC Number

169505

Preferred_Name

Methamphetamine Hydrochloride

prefixIRI

Thesaurus:C47609

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0282233

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47795

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