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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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Preferred Name | Fluphenazine | |
Synonyms |
FLUPHENAZINE Fluphenazine fluphenazine 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-(9CI) |
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Definitions |
A phenothiazine with antipsychotic activity. Fluphenazine exerts its actions by blocking postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia. This prevents the actions of dopamine, thereby reducing the hallucinations and delusions that are associated with schizophrenia. |
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ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47536 |
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ALT_DEFINITION |
A drug that is used to treat mental and emotional disorders and is being studied in the treatment of multiple myeloma. Fluphenazine may stop tumor growth by keeping myeloma cells from dividing and causing them to die. It is a type of antipsychotic.
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CAS_Registry |
69-23-8
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CHEBI_ID |
CHEBI:5123
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Chemical_Formula |
C22H26F3N3OS
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code |
C47536
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Concept_In_Subset | ||
Contributing_Source |
FDA
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DEFINITION |
A phenothiazine with antipsychotic activity. Fluphenazine exerts its actions by blocking postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia. This prevents the actions of dopamine, thereby reducing the hallucinations and delusions that are associated with schizophrenia.
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FDA_UNII_Code |
S79426A41Z
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FULL_SYN |
FLUPHENAZINE Fluphenazine fluphenazine 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-(9CI)
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Has_Salt_Form | ||
label |
Fluphenazine
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Legacy Concept Name |
Fluphenazine
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NSC Number |
62323
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Preferred_Name |
Fluphenazine
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prefixIRI |
Thesaurus:C47536
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Semantic_Type |
Pharmacologic Substance
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UMLS_CUI |
C0016368
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subClassOf |
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