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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Clomipramine Hydrochloride | |
| Synonyms |
Clomipramine Hydrochloride 3-Chloroimipramine Hydrochloride 3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine monohydrochloride CLOMIPRAMINE HYDROCHLORIDE Anafranil |
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| Definitions |
The hydrochloride salt form of clomipramine, a tertiary amine salt derivative of dibenzazepine. Clomipramine hydrochloride is a tricyclic antidepressant that acts by reducing the re-uptake of norepinephrine and serotonin in the central nervous system, thereby enhancing the effects of these neurotransmitters. This drug also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which are responsible for the many side effects seen with this agent. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47458 |
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| CAS_Registry |
17321-77-6
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|
| CHEBI_ID |
CHEBI:3755
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| Chemical_Formula |
C19H23ClN2.HCl
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|
| code |
C47458
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| Concept_In_Subset | ||
| Contributing_Source |
FDA
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| DEFINITION |
The hydrochloride salt form of clomipramine, a tertiary amine salt derivative of dibenzazepine. Clomipramine hydrochloride is a tricyclic antidepressant that acts by reducing the re-uptake of norepinephrine and serotonin in the central nervous system, thereby enhancing the effects of these neurotransmitters. This drug also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which are responsible for the many side effects seen with this agent.
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| FDA_UNII_Code |
2LXW0L6GWJ
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|
| FULL_SYN |
Clomipramine Hydrochloride 3-Chloroimipramine Hydrochloride 3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine monohydrochloride CLOMIPRAMINE HYDROCHLORIDE Anafranil
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Clomipramine Hydrochloride
|
|
| Legacy Concept Name |
Clomipramine_Hydrochloride
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|
| NSC Number |
169865
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|
| Preferred_Name |
Clomipramine Hydrochloride
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|
| prefixIRI |
Thesaurus:C47458
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0282107
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| subClassOf |
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