National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Ephedrine
Synonyms

[R-(R*,S*)]-alpha-[1-(Methylamino)ethyl]benzenemethanol

(-)-Ephedrine

EPHEDRINE

Ephedrine

Definitions

An alkaloid that is an hydroxylated form of phenethylamineand sympathomimetic amine, with potential bronchodilatory and anti-hypotensive activities. Following administration, ephedrine activates post-synaptic noradrenergic receptors. Activation of alpha-adrenergic receptors in the vasculature induces vasoconstriction, and activation of beta-adrenergic receptors in the lungs leads to bronchodilation.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C472

CAS_Registry

299-42-3

CHEBI_ID

CHEBI:15407

Chemical_Formula

C10H15NO

code

C472

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An alkaloid that is an hydroxylated form of phenethylamineand sympathomimetic amine, with potential bronchodilatory and anti-hypotensive activities. Following administration, ephedrine activates post-synaptic noradrenergic receptors. Activation of alpha-adrenergic receptors in the vasculature induces vasoconstriction, and activation of beta-adrenergic receptors in the lungs leads to bronchodilation.

FDA_UNII_Code

GN83C131XS

FULL_SYN

[R-(R*,S*)]-alpha-[1-(Methylamino)ethyl]benzenemethanol

(-)-Ephedrine

EPHEDRINE

Ephedrine

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C72765

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75031

label

Ephedrine

Legacy Concept Name

Ephedrine

NSC Number

8971

Preferred_Name

Ephedrine

prefixIRI

Thesaurus:C472

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0014479

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C87053

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_15407 DRON LOOM
http://purl.bioontology.org/ontology/ATC/S01FB02 ATC LOOM
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571345044435365930 ACVD_ONTOLOGY LOOM
http://purl.bioontology.org/ontology/RXNORM/3966 RXNORM LOOM
http://purl.jp/bio/4/id/200906051360748618 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/LP16128-8 LOINC LOOM
http://purl.obolibrary.org/obo/NCIT_C472 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0014479 OCHV LOOM
https://go.drugbank.com/drugs/DB01364 MDM LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147478 NDFRT LOOM
http://purl.obolibrary.org/obo/OMIT_0006047 OMIT LOOM
http://purl.bioontology.org/ontology/CSP/2268-6732 CRISP LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387358007 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/NDDF/001820 NDDF LOOM
http://purl.obolibrary.org/obo/dinto_DB01364 DINTO LOOM
http://stirdf.jst.go.jp/id/200907069262122174 IOBC LOOM
http://purl.bioontology.org/ontology/ATC/R01AB05 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4019279 VANDF LOOM
http://purl.bioontology.org/ontology/ATC/R01AA03 ATC LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_c9bd863f_3bb1_46f4_a9d2_f7d5047404f1 STO-DRAFT LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_c9bd863f_3bb1_46f4_a9d2_f7d5047404f1 CVAO LOOM
http://www.drugbank.ca/drugs/DB01364 FTC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.471.683.430 RH-MESH LOOM
http://purl.obolibrary.org/obo/MESH_D004809 BERO LOOM
http://purl.bioontology.org/ontology/ATC/R03CA02 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D004809 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/x01D6 RCD LOOM
http://www.co-ode.org/ontologies/galen#Ephedrine GALEN LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Ephedrine APAONTO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#4537 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_15407 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_15407 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_15407 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_15407 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_15407 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_15407 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_15407 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_15407 ECTO LOOM
http://purl.bioontology.org/ontology/SNMI/C-68050 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.033.755.624.302 RH-MESH LOOM
http://bmi.utah.edu/ontologies/hfontology/C0014479 HFO LOOM
rgo:35399 GAMUTS LOOM
http://purl.bioontology.org/ontology/MESH/D004809 MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015660 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.033.100.624.302 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/C01CA26 ATC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU060557 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.063.624.302 RH-MESH LOOM