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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Ciprofloxacin | |
| Synonyms |
ciprofloxacin Ciprofloxacin 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid CIPROFLOXACIN Cipro |
|
| Definitions |
A synthetic broad spectrum fluoroquinolone antibiotic. Ciprofloxacin binds to and inhibits bacterial DNA gyrase, an enzyme essential for DNA replication. This agent is more active against Gram-negative bacteria than Gram-positive bacteria. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C375 |
|
| Accepted_Therapeutic_Use_For |
Inhaled anthrax, post-exposure; Susceptible infectious diseases
|
|
| ALT_DEFINITION |
A drug that is used to treat infections caused by bacteria and is being studied in the treatment of bladder cancer. Cipro is a type of fluoroquinolone.
|
|
| CAS_Registry |
85721-33-1
|
|
| CHEBI_ID |
CHEBI:100241
|
|
| Chemical_Formula |
C17H18FN3O3
|
|
| code |
C375
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 |
|
| Contributing_Source |
FDA HemOnc
|
|
| DEFINITION |
A synthetic broad spectrum fluoroquinolone antibiotic. Ciprofloxacin binds to and inhibits bacterial DNA gyrase, an enzyme essential for DNA replication. This agent is more active against Gram-negative bacteria than Gram-positive bacteria. (NCI04)
|
|
| FDA_UNII_Code |
5E8K9I0O4U
|
|
| FULL_SYN |
ciprofloxacin Ciprofloxacin 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid CIPROFLOXACIN Cipro
|
|
| Has_Salt_Form | ||
| label |
Ciprofloxacin
|
|
| Legacy Concept Name |
Ciprofloxacin
|
|
| NCI_Drug_Dictionary_ID |
40784
|
|
| PDQ_Closed_Trial_Search_ID |
40784
|
|
| PDQ_Open_Trial_Search_ID |
40784
|
|
| Preferred_Name |
Ciprofloxacin
|
|
| prefixIRI |
Thesaurus:C375
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic
|
|
| UMLS_CUI |
C0008809
|
|
| subClassOf |
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