Preferred Name |
Ceramide |
|
Synonyms |
N-Acyl Sphingosine Ceramide (lipids) Ceramide ceramide |
|
Definitions |
One of a number of a class of sphingolipids, N-acyl derivatives with long chains. Ceramide is the core molecule for the synthesis of sphingomyelin, an essential lipid for myelination and neurotransmission; it may function as a second messenger to stimulate differentiation, inhibit proliferation, and induce apoptosis. (NCI04) |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C359 |
|
ALT_DEFINITION |
A type of lipid (fat) found in the membranes of cells and the covers of nerves. Some ceramides are important in signal transduction (the process by which a cell responds to substances in its environment) and may cause some types of cells to die. Ceramides are being studied in the treatment of cancer. |
|
CAS_Registry |
104404-17-3 |
|
CHEBI_ID |
CHEBI:17761 |
|
code |
C359 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 |
|
Contributing_Source |
CTRP |
|
DEFINITION |
One of a number of a class of sphingolipids, N-acyl derivatives with long chains. Ceramide is the core molecule for the synthesis of sphingomyelin, an essential lipid for myelination and neurotransmission; it may function as a second messenger to stimulate differentiation, inhibit proliferation, and induce apoptosis. (NCI04) |
|
Display_Name |
Ceramide |
|
FULL_SYN |
N-Acyl Sphingosine Ceramide (lipids) Ceramide ceramide |
|
label |
Ceramide |
|
Legacy Concept Name |
Ceramide |
|
NCI_Drug_Dictionary_ID |
38167 |
|
NSC Number |
720500 |
|
PDQ_Closed_Trial_Search_ID |
38167 |
|
PDQ_Open_Trial_Search_ID |
38167 |
|
Preferred_Name |
Ceramide |
|
prefixIRI |
Thesaurus:C359 |
|
Semantic_Type |
Organic Chemical Biologically Active Substance |
|
UMLS_CUI |
C0007745 |
|
subClassOf |