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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Ceramide | |
| Synonyms |
N-Acyl Sphingosine Ceramide (lipids) Ceramide ceramide |
|
| Definitions |
One of a number of a class of sphingolipids, N-acyl derivatives with long chains. Ceramide is the core molecule for the synthesis of sphingomyelin, an essential lipid for myelination and neurotransmission; it may function as a second messenger to stimulate differentiation, inhibit proliferation, and induce apoptosis. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C359 |
|
| ALT_DEFINITION |
A type of lipid (fat) found in the membranes of cells and the covers of nerves. Some ceramides are important in signal transduction (the process by which a cell responds to substances in its environment) and may cause some types of cells to die. Ceramides are being studied in the treatment of cancer.
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|
| CAS_Registry |
104404-17-3
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|
| CHEBI_ID |
CHEBI:17761
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|
| code |
C359
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 |
|
| Contributing_Source |
CTRP
|
|
| DEFINITION |
One of a number of a class of sphingolipids, N-acyl derivatives with long chains. Ceramide is the core molecule for the synthesis of sphingomyelin, an essential lipid for myelination and neurotransmission; it may function as a second messenger to stimulate differentiation, inhibit proliferation, and induce apoptosis. (NCI04)
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|
| Display_Name |
Ceramide
|
|
| FULL_SYN |
N-Acyl Sphingosine Ceramide (lipids) Ceramide ceramide
|
|
| label |
Ceramide
|
|
| Legacy Concept Name |
Ceramide
|
|
| NCI_Drug_Dictionary_ID |
38167
|
|
| NSC Number |
720500
|
|
| PDQ_Closed_Trial_Search_ID |
38167
|
|
| PDQ_Open_Trial_Search_ID |
38167
|
|
| Preferred_Name |
Ceramide
|
|
| prefixIRI |
Thesaurus:C359
|
|
| Semantic_Type |
Organic Chemical Biologically Active Substance
|
|
| UMLS_CUI |
C0007745
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|
| subClassOf |
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