National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Granular Cell Tumor
Synonyms

Granular Cell Myoblastoma

Abrikossoff's Tumor

Abrikossoff Tumor

Granular Cell Nerve Sheath Tumor

Granular Cell Schwannoma

Granular Cell Tumor

Granular cell tumor, NOS

Definitions

An unusual benign or malignant neoplasm characterized by the presence of neoplastic large polygonal cells with granular, eosinophilic cytoplasm which contains abundant lysosomes. It was originally thought to be a tumor originating from muscle cells and was named granular cell myoblastoma. Subsequent studies have suggested a derivation from Schwann cells. It affects females more often than males and it usually presents as a solitary mass. A minority of patients have multiple tumors. It can arise from many anatomic sites including the posterior pituitary gland, skin, oral cavity, esophagus, stomach, heart, mediastinum, and breast.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3474

code

C3474

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168661

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168656

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168662

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168658

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126659

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168655

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168657

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

Contributing_Source

GDC

DEFINITION

An unusual benign or malignant neoplasm characterized by the presence of neoplastic large polygonal cells with granular, eosinophilic cytoplasm which contains abundant lysosomes. It was originally thought to be a tumor originating from muscle cells and was named granular cell myoblastoma. Subsequent studies have suggested a derivation from Schwann cells. It affects females more often than males and it usually presents as a solitary mass. A minority of patients have multiple tumors. It can arise from many anatomic sites including the posterior pituitary gland, skin, oral cavity, esophagus, stomach, heart, mediastinum, and breast.

FULL_SYN

Granular Cell Myoblastoma

Abrikossoff's Tumor

Abrikossoff Tumor

Granular Cell Nerve Sheath Tumor

Granular Cell Schwannoma

Granular Cell Tumor

Granular cell tumor, NOS

ICD-O-3_Code

9580/0

Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177621

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176985

label

Granular Cell Tumor

Legacy Concept Name

Granular_Cell_Tumor

Maps_To

Granular cell myoblastoma, NOS

Granular cell tumor, NOS

9580/0

Neoplastic_Status

Undetermined

Preferred_Name

Granular Cell Tumor

prefixIRI

Thesaurus:C3474

Semantic_Type

Neoplastic Process

UMLS_CUI

C0085167

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4972

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/MONDO_0006235 MONDO LOOM
http://purl.bioontology.org/ontology/MEDDRA/10060982 MEDDRA LOOM
rgo:13076 GAMUTS LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Granular_Cell_Tumor CSEO LOOM
http://www.owl-ontologies.com/unnamed.owl#RID17873 DERMLEX LOOM
http://purl.obolibrary.org/obo/MPATH_569 MPATH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/404035005 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/NCIT_C3474 BERO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00037872 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/12169001 SNOMEDCT LOOM
http://id.nlm.nih.gov/mesh/D016586 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C04.557.450.590.350 RH-MESH LOOM
http://purl.jp/bio/4/id/200906073751074070 IOBC LOOM
http://purl.obolibrary.org/obo/DOID_2411 DOID LOOM
http://purl.obolibrary.org/obo/DOID_2411 BAO LOOM
http://purl.obolibrary.org/obo/DOID_2411 HHEAR LOOM
http://purl.obolibrary.org/obo/DOID_2411 DDSS LOOM
http://purl.obolibrary.org/obo/DOID_2411 NIFSTD LOOM
http://purl.obolibrary.org/obo/DOID_2411 MIDO LOOM
http://purl.obolibrary.org/obo/DOID_2411 FNS-H LOOM
http://www.owl-ontologies.com/NPOntology.owl#DOID_2411 NATPRO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#15475 OCHV LOOM
http://purl.obolibrary.org/obo/OMIT_0017058 OMIT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0085167 OCHV LOOM
http://purl.obolibrary.org/obo/MPATH_413 MPATH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D016586 RH-MESH LOOM
http://www.ebi.ac.uk/efo/EFO_1000284 CCONT LOOM
http://www.ebi.ac.uk/efo/EFO_1000284 EFO LOOM
http://www.ebi.ac.uk/efo/EFO_1000284 EFO LOOM
http://purl.obolibrary.org/obo/DERMO_0001086 DERMO LOOM
http://purl.obolibrary.org/obo/MONDO_0006235 MONDO LOOM
http://purl.obolibrary.org/obo/MONDO_0006235 DOVES LOOM
http://purl.bioontology.org/ontology/MESH/D016586 MESH LOOM