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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Patent Foramen Ovale | |
| Synonyms |
Patent Foramen Ovale |
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| Definitions |
A persistent opening in the atrial septum after birth. While a normal part of fetal circulation, the foramen ovale should close once the newborn begins breathing and the pressure in the left atrium exceeds that of the right atrium. While a PFO is generally asymptomatic, it can lead to the passage of clots from the venous circulation into the artierial circulation, resulting in paradoxical emboli, and possible strokes. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34619 |
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| code |
C34619
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| DEFINITION |
A persistent opening in the atrial septum after birth. While a normal part of fetal circulation, the foramen ovale should close once the newborn begins breathing and the pressure in the left atrium exceeds that of the right atrium. While a PFO is generally asymptomatic, it can lead to the passage of clots from the venous circulation into the artierial circulation, resulting in paradoxical emboli, and possible strokes.
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| FULL_SYN |
Patent Foramen Ovale
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| label |
Patent Foramen Ovale
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| Legacy Concept Name |
Patent_Foramen_Ovale
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| Preferred_Name |
Patent Foramen Ovale
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| prefixIRI |
Thesaurus:C34619
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| Semantic_Type |
Disease or Syndrome Congenital Abnormality
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| UMLS_CUI |
C4229431
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| subClassOf |
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