loading...| Preferred Name |
Glioblastoma |
|
| Synonyms |
Glioblastoma glioblastoma Glioblastoma multiforme CNS, glioblastoma (GBM) Glioblastoma Multiforme glioblastoma multiforme Spongioblastoma multiforme GBM (Glioblastoma) Spongioblastoma Multiforme GBM |
|
| Definitions |
The most malignant astrocytic tumor (WHO grade 4). It is composed of poorly differentiated neoplastic astrocytes and is characterized by the presence of cellular polymorphism, nuclear atypia, brisk mitotic activity, vascular thrombosis, microvascular proliferation, and necrosis. It typically affects adults and is preferentially located in the cerebral hemispheres. (Adapted from WHO) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3058 |
|
| ALT_DEFINITION |
A fast-growing type of central nervous system tumor that forms from glial (supportive) tissue of the brain and spinal cord and has cells that look very different from normal cells. GBM usually occurs in adults and affects the brain more often than the spinal cord. |
|
| code |
C3058 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138190 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168661 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168656 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168662 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159328 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156966 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168658 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159335 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103031 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C192842 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126659 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165258 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102905 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168655 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C138188 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158520 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156953 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159420 |
|
| Contributing_Source |
Cellosaurus CPTAC CTEP GDC |
|
| DEFINITION |
The most malignant astrocytic tumor (WHO grade 4). It is composed of poorly differentiated neoplastic astrocytes and is characterized by the presence of cellular polymorphism, nuclear atypia, brisk mitotic activity, vascular thrombosis, microvascular proliferation, and necrosis. It typically affects adults and is preferentially located in the cerebral hemispheres. (Adapted from WHO) |
|
| DesignNote |
Glioblastoma is not an astrocytoma. It is an astrocytic tumor. The latter includes astrocytomas and glioblastomas. However, when an anaplastic astrocytoma progresses to grade IV tumor, it is called a glioblastoma. |
|
| FULL_SYN |
Glioblastoma glioblastoma Glioblastoma multiforme CNS, glioblastoma (GBM) Glioblastoma Multiforme glioblastoma multiforme Spongioblastoma multiforme GBM (Glioblastoma) Spongioblastoma Multiforme GBM |
|
| ICD-O-3_Code |
9440/3 |
|
| Is_Value_For_GDC_Property |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177615 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177584 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177621 |
|
| label |
Glioblastoma |
|
| Legacy Concept Name |
Glioblastoma |
|
| Maps_To |
Glioblastoma Glioblastoma, NOS Glioblastoma multiforme CNS, glioblastoma (GBM) Spongioblastoma multiforme 01 02 03 04 10 20 62 9440/3 |
|
| Neoplasm_Has_Special_Category | ||
| Neoplastic_Status |
Malignant |
|
| Preferred_Name |
Glioblastoma |
|
| prefixIRI |
Thesaurus:C3058 |
|
| Semantic_Type |
Neoplastic Process |
|
| UMLS_CUI |
C0017636 |
|
| subClassOf |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102897 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36025 |