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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Nizatidine | |
| Synonyms |
Axid NIZATIDINE Nizatidine |
|
| Definitions |
A competitive and reversible histamine H2-receptor antagonist with antacid activity. Nizatidine inhibits the histamine H2-receptors located on the basolateral membrane of the gastric parietal cell, thereby reducing basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29295 |
|
| CAS_Registry |
76963-41-2
|
|
| Chemical_Formula |
C12H21N5O2S2
|
|
| code |
C29295
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
A competitive and reversible histamine H2-receptor antagonist with antacid activity. Nizatidine inhibits the histamine H2-receptors located on the basolateral membrane of the gastric parietal cell, thereby reducing basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli.
|
|
| FDA_UNII_Code |
P41PML4GHR
|
|
| FULL_SYN |
Axid NIZATIDINE Nizatidine
|
|
| label |
Nizatidine
|
|
| Legacy Concept Name |
Nizatidine
|
|
| Preferred_Name |
Nizatidine
|
|
| prefixIRI |
Thesaurus:C29295
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0085154
|
|
| subClassOf |
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