National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Nefazodone Hydrochloride

Synonyms

Nefazodone Hydrochloride

NEFAZODONE HYDROCHLORIDE

Nefazadone HCl

Serzone

Definitions

A synthetic derivative of phenylpiperazine and chemically unrelated to selective serotonin reuptake inhibitors, tricyclics, tetracyclics, or monoamine oxidase inhibitors (MAOI), antidepressant Nefazadone Hydrochloride antagonizes central 5-HT2 receptors and inhibits reuptake of serotonin and norepinephrine. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29283

ALT_DEFINITION

A drug used to treat depression. It belongs to the family of drugs called antidepressant agents.

CAS_Registry

82752-99-6

CHEBI_ID

CHEBI:7495

Chemical_Formula

C25H32ClN5O2.HCl

code

C29283

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic derivative of phenylpiperazine and chemically unrelated to selective serotonin reuptake inhibitors, tricyclics, tetracyclics, or monoamine oxidase inhibitors (MAOI), antidepressant Nefazadone Hydrochloride antagonizes central 5-HT2 receptors and inhibits reuptake of serotonin and norepinephrine. (NCI04)

FDA_UNII_Code

27X63J94GR

FULL_SYN

Nefazodone Hydrochloride

NEFAZODONE HYDROCHLORIDE

Nefazadone HCl

Serzone

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61859

label

Nefazodone Hydrochloride

Legacy Concept Name

Nefazadone_Hydrochloride

Preferred_Name

Nefazodone Hydrochloride

prefixIRI

Thesaurus:C29283

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0771310

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C265

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