National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Preferred Name

6-Azauridine
Synonyms

6-Azauracilriboside

6-Azauridine

1,2,4-triazine-3,5(2H,4H)-dione, 2-beta-D-ribofuranosyl

6-azauracilriboside

6-azauracil 1-riboside

3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine riboside

2-beta-D-ribofuranosyl-1,2,4-triazine-3,5(2H, 4H)-dione

6-azauracil riboside

Riboazauracil

6-AZAURIDINE

2-beta-D-ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione

6-azauracil-beta-D-riboside

6-Azauracil riboside

6-Azauracil 1-riboside

6-Azauracil-.beta.-D-riboside

Azauridine
Definitions

A synthetic triazine analogue of uridine with antimetabolite activity. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis.
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C291
CAS_Registry

54-25-1
CHEBI_ID

CHEBI:35668
code

C291
Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923
Contributing_Source

FDA
DEFINITION

A synthetic triazine analogue of uridine with antimetabolite activity. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis.
FDA_UNII_Code

7BVB29RCPR
FULL_SYN

6-Azauracilriboside

6-Azauridine

1,2,4-triazine-3,5(2H,4H)-dione, 2-beta-D-ribofuranosyl

6-azauracilriboside

6-azauracil 1-riboside

3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine riboside

2-beta-D-ribofuranosyl-1,2,4-triazine-3,5(2H, 4H)-dione

6-azauracil riboside

Riboazauracil

6-AZAURIDINE

2-beta-D-ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione

6-azauracil-beta-D-riboside

6-Azauracil riboside

6-Azauracil 1-riboside

6-Azauracil-.beta.-D-riboside

Azauridine
label

6-Azauridine
Legacy Concept Name

_6-Azauridine
NCI_Drug_Dictionary_ID

39158
NSC Number

32074
PDQ_Closed_Trial_Search_ID

39158
PDQ_Open_Trial_Search_ID

39158
Preferred_Name

6-Azauridine
prefixIRI

Thesaurus:C291
Semantic_Type

Pharmacologic Substance

Nucleic Acid, Nucleoside, or Nucleotide
UMLS_CUI

C0004483
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2170

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1557
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