Link to this page
National Cancer Institute Thesaurus
| Preferred Name | Fluvoxamine Maleate | |
| Synonyms |
FLUVOXAMINE MALEATE Fluvoxamine Maleate Fluoxamine Luvox |
|
| Definitions |
The maleate salt form of fluvoxamine, a 2-aminoethyl oxime ether of aralkylketones, with antidepressant, antiobsessive-compulsive, and antibulimic activities. Fluvoxamine blocks serotonin reuptake by inhibiting the serotonin reuptake pump of the presynaptic neuronal membrane leading to an increase of serotonin levels within the synaptic cleft. This results in facilitated serotonergic transmission and decreased serotonin turnover leading to antidepressant and antiobsessive-compulsive effects. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29063 |
|
| ALT_DEFINITION |
A drug used to treat obsessive-compulsive disorder. It is a type of antidepressant agent and selective serotonin reuptake inhibitor (SSRI).
|
|
| CAS_Registry |
61718-82-9
|
|
| Chemical_Formula |
C15H21F3N2O2.C4H4O4
|
|
| code |
C29063
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA
|
|
| DEFINITION |
The maleate salt form of fluvoxamine, a 2-aminoethyl oxime ether of aralkylketones, with antidepressant, antiobsessive-compulsive, and antibulimic activities. Fluvoxamine blocks serotonin reuptake by inhibiting the serotonin reuptake pump of the presynaptic neuronal membrane leading to an increase of serotonin levels within the synaptic cleft. This results in facilitated serotonergic transmission and decreased serotonin turnover leading to antidepressant and antiobsessive-compulsive effects.
|
|
| Display_Name |
Fluvoxamine Maleate
|
|
| FDA_UNII_Code |
5LGN83G74V
|
|
| FULL_SYN |
FLUVOXAMINE MALEATE Fluvoxamine Maleate Fluoxamine Luvox
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Fluvoxamine Maleate
|
|
| Legacy Concept Name |
Fluvoxamine_Maleate
|
|
| NCI_Drug_Dictionary_ID |
735770
|
|
| PDQ_Closed_Trial_Search_ID |
735770
|
|
| PDQ_Open_Trial_Search_ID |
735770
|
|
| Preferred_Name |
Fluvoxamine Maleate
|
|
| prefixIRI |
Thesaurus:C29063
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0700473
|
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |