National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Pernicious Anemia
Synonyms

Pernicious Anemia

Intrinsic Factor Deficiency

Vitamin B12 deficiency anemia due to intrinsic factor deficiency

pernicious anemia

Definitions

Megaloblastic anemia caused by vitamin B-12 deficiency due to impaired absorption. The impaired absorption of vitamin B-12 is secondary to atrophic gastritis and loss of gastric parietal cells.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2871

ALT_DEFINITION

Megaloblastic anemia caused by vitamin B12 deficiency due to insufficient production of intrinsic factor by gastric parietal cells, which is essential for adequate absorption of vitamin B12. It is classically characterized by weakness and fatigue, glossitis, and paresthesias.

A type of anemia (low red blood cell count) caused by the body's inability to absorb vitamin B12.

code

C2871

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C193183

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132009

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C193006

Contributing_Source

NICHD

mCode

DEFINITION

Megaloblastic anemia caused by vitamin B-12 deficiency due to impaired absorption. The impaired absorption of vitamin B-12 is secondary to atrophic gastritis and loss of gastric parietal cells.

FULL_SYN

Pernicious Anemia

Intrinsic Factor Deficiency

Vitamin B12 deficiency anemia due to intrinsic factor deficiency

pernicious anemia

label

Pernicious Anemia

Legacy Concept Name

Pernicious_Anemia

Preferred_Name

Pernicious Anemia

prefixIRI

Thesaurus:C2871

Related_To_Genetic_Biomarker

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C203622

Semantic_Type

Disease or Syndrome

UMLS_CUI

C0002892

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C34382

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