loading...| Preferred Name |
Tyrosine Kinase Inhibitor |
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| Synonyms |
Protein Tyrosine Kinase Inhibitors Tyrosine Kinase Inhibitor tyrosine kinase inhibitor TK Inhibitors PTK Inhibitors |
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| Definitions |
Any substance that inhibits tyrosine kinase, an enzyme involved in the transduction and processing of many extracellular and intracellular signals including cell proliferation. Inhibition of tyrosine kinase may result in inhibition of cell growth and cell proliferation. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1967 |
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| ALT_DEFINITION |
A drug that interferes with cell communication and growth and may prevent tumor growth. Some tyrosine kinase inhibitors are used to treat cancer. |
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| CHEBI_ID |
CHEBI:38637 |
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| code |
C1967 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
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| Contributing_Source |
CTRP GDC |
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| DEFINITION |
Any substance that inhibits tyrosine kinase, an enzyme involved in the transduction and processing of many extracellular and intracellular signals including cell proliferation. Inhibition of tyrosine kinase may result in inhibition of cell growth and cell proliferation. |
|
| Display_Name |
Tyrosine Kinase Inhibitor |
|
| FULL_SYN |
Protein Tyrosine Kinase Inhibitors Tyrosine Kinase Inhibitor tyrosine kinase inhibitor TK Inhibitors PTK Inhibitors |
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| Is_Value_For_GDC_Property | ||
| label |
Tyrosine Kinase Inhibitor |
|
| Legacy Concept Name |
Tyrosine_Kinase_Inhibitor |
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| Maps_To |
Tyrosine Kinase Inhibitor |
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| Preferred_Name |
Tyrosine Kinase Inhibitor |
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| prefixIRI |
Thesaurus:C1967 |
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| Semantic_Type |
Chemical Viewed Functionally |
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| UMLS_CUI |
C1268567 |
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| subClassOf |