loading...| Preferred Name |
Fibronectin |
|
| Synonyms |
Fibronectin Isoform 1 Isoform 1 Fibronectin Large External Transformation-Sensitive Protein Fibronectin Cold-Insoluble Globulin Large, External, Transformation-Sensitive Protein LETS Protein Fibronectin 1 CIG FN FN1 FNZ LETS |
|
| Definitions |
Fibronectin (2386 aa, ~263 kDa) is encoded by the human FN1 gene. This protein is involved in cell adhesion- and migration-dependent processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16581 |
|
| code |
C16581 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP |
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| DEFINITION |
Fibronectin (2386 aa, ~263 kDa) is encoded by the human FN1 gene. This protein is involved in cell adhesion- and migration-dependent processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. |
|
| DesignNote |
Fibronectin can be cleaved to form Ugl-Y1, Ugl-Y2, Ugl-Y3 and anastellin. (UniProt) Anastellin is a 76 amino acid fragment from carboxy-terminal portion of the first fibronectin type-III domain with potential antiangiogenic activity. Anastellin binds fibronectin and induces fibril formation; the resulting fibronectin polymer, superfibronectin, exhibits enhanced adhesive properties and may also inhibit angiogenesis. (UniProt) |
|
| Display_Name |
Fibronectin |
|
| FULL_SYN |
Fibronectin Isoform 1 Isoform 1 Fibronectin Large External Transformation-Sensitive Protein Fibronectin Cold-Insoluble Globulin Large, External, Transformation-Sensitive Protein LETS Protein Fibronectin 1 CIG FN FN1 FNZ LETS |
|
| label |
Fibronectin |
|
| Legacy Concept Name |
Fibronectin |
|
| NCI_META_CUI |
CL1379609 |
|
| OMIM_Number |
135600 |
|
| Preferred_Name |
Fibronectin |
|
| prefixIRI |
Thesaurus:C16581 |
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| Semantic_Type |
Amino Acid, Peptide, or Protein |
|
| Swiss_Prot |
P02751 |
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| subClassOf |