National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

ELISA
Synonyms

enzyme-linked immunosorbent assay

Enzyme-linked Immunosorbent Assay

ELISA

Definitions

A highly sensitive technique for detecting and measuring antigens or antibodies in a solution; the solution is run over a surface to which immobilized antibodies specific to the substance have been attached, and if the substance is present, it will bind to the antibody layer, and its presence is verified and visualized with an application of antibodies that have been tagged in some way. (BioTech Life Science Dictionary)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16553

ALT_DEFINITION

A type of enzyme immunoassay in which an antigen or antibody is bound to a solid substrate (e.g., microplate or beads) and interacts with an enzyme-linked antibody or antigen in solution.

A laboratory technique that uses antibodies linked to enzymes to detect and measure the amount of a substance in a solution, such as serum. The test is done using a solid surface to which the antibodies and other molecules stick. In the final step, an enzyme reaction takes place that causes a color change that can be read using a special machine. There are many different ways that an ELISA can be done. ELISAs may be used to help diagnose certain diseases.

code

C16553

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179027

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118169

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C85492

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189083

Contributing_Source

CDISC

CTRP

SeroNet

DEFINITION

A highly sensitive technique for detecting and measuring antigens or antibodies in a solution; the solution is run over a surface to which immobilized antibodies specific to the substance have been attached, and if the substance is present, it will bind to the antibody layer, and its presence is verified and visualized with an application of antibodies that have been tagged in some way. (BioTech Life Science Dictionary)

Display_Name

ELISA

FULL_SYN

enzyme-linked immunosorbent assay

Enzyme-linked Immunosorbent Assay

ELISA

label

ELISA

Legacy Concept Name

ELISA

Preferred_Name

ELISA

prefixIRI

Thesaurus:C16553

Semantic_Type

Laboratory Procedure

UMLS_CUI

C0014441

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17455

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